Earlier this month, the family of a deceased Florida woman told local news outlets that doctors said she died from the mosquito-borne illness dengue fever.
This death was likely part of a larger dengue outbreak in Hillsborough County, Florida, where there have been 95 documented cases of dengue since July 2026.
While the Florida Department of Health has not yet confirmed the woman’s official cause of death, the Hillsborough County Health Department had issued a mosquito-borne illness alert in August due to reports of multiple locally acquired cases of dengue fever.
This cluster of locally spread cases is a stark reminder that a disease which most Americans associate with faraway tropical vacations is increasingly being caught at home.
Dengue is often called ‘breakbone fever,’ and the nickname is earned.
People who get sick typically develop a sudden high fever along with a pounding headache, pain behind the eyes and deep aches in the muscles, joints and bones.
Many also feel nauseated, throw up or break out in a blotchy rash a few days in.
But because it is often travel-associated, dengue fever can easily slip past both patients and doctors. In parts of the US where the disease is still uncommon, it is easily mistaken for the flu or COVID-19, and that delay in diagnosis and treatment can be dangerous.
Dengue fever spreads through the bite of infected Aedes mosquitoes, mainly the Aedes aegypti (pictured above), a species commonly found in Florida
How it spreads
Dengue is not passed from person to person like a cold. It spreads through the bite of infected Aedes mosquitoes, mainly Aedes aegypti, a species commonly found in Florida.
These mosquitoes thrive in warm cities and can breed in as little as a bottle capful of standing water. These mosquitoes bite during the day, not just at dusk.
The cycle is simple and hard to break: A mosquito bites an infected person, then bites someone else days later, giving them the virus.
Dengue is especially tricky because most infections cause no symptoms at all. Roughly three in four people who catch the virus never feel sick. For the 25 percent who are symptomatic, those symptoms don’t appear until four to 10 days after being bitten.
In addition, there are four different strains of the dengue virus, and surviving one gives you lasting protection against only that one. A second infection with a different type actually raises the odds of severe disease.
A life-threatening turn
Most people suffer with dengue for a miserable week and then recover on their own.
But about one in 20 patients progress to severe dengue, a life-threatening turn that tends to strike just as the fever breaks – often around days three to seven, when patients and their families may wrongly assume the worst is over.
In severe dengue, tiny blood vessels throughout the body start leaking fluid, blood pressure can crash and dangerous bleeding or organ damage can follow.
Warning signs that someone is sliding into this phase include severe belly pain, repeated vomiting, bleeding from the gums or nose, extreme drowsiness or restlessness, and blood in vomit or stool.
Some groups face higher risk, including infants, pregnant women, adults over 65 and people with conditions like diabetes, obesity or kidney disease.
Left untreated, severe dengue can kill up to 10 percent of patients. With prompt hospital care, that number drops below one in 100 – which is why recognizing it early matters so much.
A dengue vaccine exists, but it is not recommended for the average American traveler. The available shots are used only in select cases, such as children who live in high-transmission areas and have already had dengue once. So prevention still rests mostly on avoiding mosquito bites.
How dengue is treated
There is no antiviral drug that cures dengue. Care is all about supporting the body while it fights the virus. For people well enough to stay home, that means rest, plenty of fluids and acetaminophen for fever and pain.
Patients who may have dengue must avoid aspirin, ibuprofen and other non-steroidal anti-inflammatory drugs. These drugs raise the risk of bleeding, which is already a danger with dengue.
Patients who develop more severe symptoms need to be admitted to the hospital, where doctors give carefully measured intravenous fluids and watch closely. Too little fluid and the patient can go into shock; too much and the lungs can flood.
A worsening global problem
Dengue is surging worldwide.
The World Health Organization recorded more than 14 million cases in 2024, its worst year on record, across some 100 countries. That’s a 2,600 percent increase from the more than 505,000 cases reported in 2000.
Warmer temperatures, rapid urban growth and global travel are all helping the mosquitoes – and the virus – expand into places where it has never been a problem before.
South Asia, Southeast Asia and Latin America carry the heaviest burden, but the map is spreading north.
There have been 346 travel-associated dengue fever cases and 73 locally acquired ones in the contiguous US, including 72 in Florida (pictured above)
Why the US should pay attention
Most US dengue cases are still picked up abroad and travelers return home sick.
In 2023 alone, the Centers for Disease Control and Prevention (CDC) reported nearly 1,900 such travel-related cases.
But every infected traveler is a spark, and in warm states the tinder is already there.
Among US territories, Puerto Rico and the US Virgin Islands see the most cases by far.
Florida has the highest risk among the 50 states, with Miami-Dade County recording more than 300 locally acquired dengue infections between 2010 and 2024.
Local cases have also turned up in Texas, California, Arizona and Hawaii.
What to do if you think you have dengue
If you develop a sudden fever after traveling to a dengue-prone area, or after mosquito exposure in South Florida, see a doctor and mention where you’ve been.
Rest, drink fluids and use acetaminophen – not ibuprofen or aspirin.
Most importantly, watch for the warning signs. Severe belly pain, repeated vomiting, bleeding or sudden drowsiness means get to an emergency room right away.
And to protect yourself and your neighbors: Use insect repellent, wear long sleeves and dump out any standing water in your yard where mosquitoes breed.
This article is adapted from The Conversation, a nonprofit news organization dedicated to sharing the knowledge of experts. It was written by Andrés Henao, a professor of medicine and infectious disease at the University of Colorado Anschutz. It was edited by Alexa Lardieri, the US health editor at the Daily Mail.
