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A spokesperson for South Wales Police has asked drivers to avoid the area and find alternative routes.
They said: “We are at the scene of a collision on the M4. The road is currently closed eastbound only between Junction 41 Baglan and Junction 42 Swansea/Fabian Way. It is expected to remain closed for some time.
“Motorists are advised to avoid the area and use alternative routes where possible. Delays are expected in the area.”
