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Health newsRecent Post

Horrifying truth about baby wipes: The hidden risks exposed by Target’s ‘reasonable probability of death’ recall

by David Jones 02/07/2026
written by David Jones

For new parents, baby wipes are a simple convenience that have become a cornerstone of modern childcare – used for everything from changing diapers and wiping sticky fingers to mopping up endless spills and messes. 

So the news that a major retailer had recalled thousands of packs of wipes due to toxic contamination likely sparked concern in millions of American households.

This week, Target voluntarily pulled its Up & Up Fragrance Free Baby Wipes and Fresh Cucumber Scented Baby Wipes from shelves after customers reported unusual discoloration – and, more worryingly, symptoms including irritation and potential infections.

FDA testing revealed the presence of bacteria that can cause serious and even life-threatening illness. 

The agency classified the recall as Class I – the most serious – given when exposure could potentially lead to severe health consequences or death.  

Consumers have been urged to stop using the wipes immediately and return them for a full refund. It remains unclear how the contamination occurred or whether anyone has fallen seriously ill.

This incident is undoubtedly worrying.

But experts warn it points to a broader issue with pre-moistened wipes: these everyday essentials may carry hidden risks far beyond a single recall, from antibiotic-resistant bacteria to so-called ‘forever chemicals’ and microplastics lurking in their fibers.

Horrifying truth about baby wipes: The hidden risks exposed by Target’s ‘reasonable probability of death’ recall

Target recalled two versions of its store-brand baby wipes

Deadly bacteria that triggered Target recall 

Burkholderia cepacia complex (Bcc), the bacteria detected in the recalled wipes, poses little risk to most healthy people – but can cause serious infections in vulnerable groups, including babies, whose immune systems are still developing. 

Symptoms can include fever, fatigue and, in more serious cases, life-threatening complications. 

Crucially, many Bcc strains are resistant to multiple antibiotics, making infections extremely difficult to treat. 

The bacteria are commonly found in soil and water, and exposure can occur through contaminated surfaces, medical equipment or person-to-person contact. 

A related species, Burkholderia gladioli, was also found in the wipes and is known to cause similar infections. 

For healthy individuals, using contaminated wipes on minor cuts or broken skin may lead only to localized irritation or infection. But in vulnerable groups such as newborns, infants and young children, the consequences can be far more severe.

According to the FDA, infections in these groups are more likely to spread into the bloodstream, potentially leading to sepsis or pneumonia. It is not yet clear how the contamination occurred, and investigations are ongoing.

Target's Up & Up Fragrance Free Baby Wipes, which were recalled

Target's Up & Up Fresh Cucumber Scented Baby Wipes, which were recalled

Target voluntarily recalled its Up & Up Fragrance Free Baby Wipes and Up & Up Fresh Cucumber Scented Baby Wipes

How contamination can happen

Disposable wipes are typically pre-moistened with purified water, but that moisture also makes them susceptible to contamination.

If the water used during manufacturing is not properly sterilized, or production equipment becomes contaminated, bacteria can spread rapidly through entire batches of wipes.

Bcc, in particular, is difficult to eliminate. 

‘Burkholderia bacteria are found naturally in the environment and are well known for being resistant to many commercially available antibiotics,’ said Dr John J LiPuma, professor emeritus of Pediatric Infectious Diseases at the University of Michigan.

‘They can also survive many common disinfectants and are notorious for contaminating a wide range of medicinal and healthcare products.’

Manufacturers add preservatives to prevent bacteria multiplying inside wipes, but contamination can still occur if the manufacturing process is compromised. 

Damage to packaging or prolonged exposure to extreme temperatures may also reduce the effectiveness of preservatives, allowing bacteria to grow.

Similar contamination incidents have occurred before. 

In 2025, Neutrogena recalled cleansing towelettes after they were found to contain Pluralibacter gergoviae. 

As with Bcc, while the bacterium poses little risk to most healthy people, it has been linked to serious infections, including sepsis, in people with weakened immune systems.

The hidden risks of ‘forever chemicals’

Beyond bacteria, experts also warn that some wipes may expose users to potentially harmful chemicals.

The Environmental Working Group (EWG) gave Target’s recalled fragrance-free wipes a low hazard score of one out of ten, indicating minimal concern. 

However, the cucumber-scented version scored higher, largely because it contains added fragrance.

That single ingredient can conceal a complex cocktail of chemicals.

‘The word “fragrance” or “parfum” on the product label represents an undisclosed mixture,’ the EWG warns, which can include substances such as diethyl phthalate.

Phthalates are commonly used to make scents last longer and are found in around three-quarters of scented personal care products.

They are also used to soften plastics, and may be found in the fabric baby wipes are made from – although these won’t be listed on the label.  

Emerging evidence suggests long-term exposure to phthalates may interfere with the body’s hormone system. Studies have linked the chemicals to reduced fertility, obesity and diabetes, while exposure during pregnancy has also been associated with babies being born at a lower birth weight. 

A 2024 review published in Science of the Total Environment found children exposed to higher levels of phthalates before birth were more likely to have poorer motor skills, weaker memory, delayed language development, and behavioral and attention problems.

Studies have also associated phthalates with cardiovascular problems, including high blood pressure, and increased inflammation. 

Researchers are also investigating whether long-term phthalate exposure could increase the risk of certain cancers, including breast, thyroid and testicular cancer, although studies in humans have yet to establish a clear link. 

The FDA has historically maintained that the levels of phthalates found in cosmetics and personal care products do not pose a safety risk. However, it has begun to reassess the chemicals’ application in other areas, including revoking the authorization of certain phthalates previously used in food-contact materials. 

Microplastics can be common in disposable baby wipes and have been linked to developmental issues in infants and young children

Microplastics can be common in disposable baby wipes and have been linked to developmental issues in infants and young children 

The microplastics problem 

Another growing concern is the materials disposable wipes are made from. Many are manufactured using plastic fibers such as polypropylene or polyester, which make them soft, strong and less likely to tear.

Each time a wipe is used, tiny fragments of these plastics – known as microplastics – can be shed. 

Because the fibers do not readily break down, they can also accumulate in the environment, where they may eventually enter the food chain.

Scientists have detected microplastics in human blood, lungs and even the placenta, although it is not yet clear what effect, if any, these particles have on human health.

Some studies have linked higher levels of microplastics with inflammation and raised concerns about possible effects on the heart and reproductive system. 

Animal research has also suggested early-life exposure could affect growth, brain development and motor function.

However, experts stress that research in humans is still at an early stage, and there is currently no conclusive evidence that exposure levels from everyday products directly cause disease.

What parents can do

With concerns mounting, consumer watchdogs say there are simple ways parents can reduce potential risks.

Consumer Reports recommends choosing fragrance-free wipes wherever possible and looking for products made from plant-based materials such as bamboo or cotton rather than plastic fibers. 

Parents can also check the ingredients list and avoid products containing phthalates or unnecessary additives.

While recalls such as Target’s remain relatively rare, experts say they are a reminder that even everyday baby products are not entirely risk-free. 

For many parents, paying closer attention to ingredients and materials may be a simple way to reduce unnecessary exposure.

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Local newsRecent Post

Large fire breaks out at Aberthaw Power Station near Barry

by David Jones 02/07/2026
written by David Jones

The blaze began at Aberthaw Power Station near Barry on July 2, and prompted warnings for nearby residents to keep their doors and windows closed.

Crews from South Wales Fire and Rescue Service were at the scene at around 10.40am and remained on site for hours as they worked to bring the fire under control.

A spokesperson for South Wales Fire and Rescue Service said: “South Wales Fire and Rescue Service is currently at the scene of a large fire at Aberthaw Power Station in Barry.  

“Residents are advised to keep windows and doors closed due to large amounts of smoke.

“The incident remains on-going, there are no further updates at this time [11.36am]”. 

(Image: Sioned Mair Boyle)

Andrew RT Davies, Conservative Senedd member for the Vale of Glamorgan and Bridgend, said: “I’m deeply concerned by the fire at the Aberthaw Power Station site – and I’d like to thank the brave firefighters at the scene who are working hard to make the area safe.

“All residents in the area should follow advice issued by authorities in the area – including to keep doors and windows closed.

“If any constituent requires further information, please do get in touch.”

A spokesperson for CCR Energy who own Aberthaw Power Station said: “The situation is currently being managed by the emergency services and our on-site teams.

“All personnel have been reported safe, and our priority is the safety and wellbeing of everyone involved.”

Residents were quick to express their shock at the fire on social media, with many hoping nobody had been injured.

One resident said: “Hope all are safe, that’s really bad”.

Another wrote: “Hope everyone is safe”.

Others expressed concern over the toxicity of the fire, emphasising South Wales Fire and Rescue Service’s warning to keep windows and doors shut.

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Art Craft and Leisure newsRecent Post

Gary Glitter charged with historical sexual offences

by David Jones 02/07/2026
written by David Jones

Gary Glitter, the former singer whose real name is Paul Gadd, has been charged with historical sexual offences dating back to 1978, the Metropolitan Police has said.

The charges relate to one count of unlawful sexual intercourse with a girl under the age of 13, and three counts of indecent assault on a girl under the age of 14.

There is one alleged victim, with the offences said to have taken place between the years of 1978-1981 at a residential address in Kensington.

Gadd is due to appear at Westminster Magistrates’ Court on 5 August.

The allegations were first reported to the Met on 9 January 2025 and an investigation into the circumstances was launched.

Gadd was first interviewed on 22 July 2025 in relation to the investigation.

The alleged victim is currently being supported by specialist officers, and they have been made aware of this update.

Glitter is currently being held in HMP Cannings Wood in Devon.

Bethan David, Deputy Chief Crown Prosecutor in CPS London, said of the charges: “This follows allegations made by a woman relating to a period of alleged abuse that took place between 1978 and 1981.

“Our prosecutors have worked to establish that there is sufficient evidence to bring this case to court and that it is in the public interest to do so.”

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Health newsRecent Post

NHS postcode lottery in cancer mental health support exposed

by David Jones 02/07/2026
written by David Jones

NHS postcode lottery in cancer mental health support exposed

For many patients, the mental health impact hits after treatment (Image: Getty)

Cancer patients in England are facing a postcode lottery for mental health support after treatment, according to research by a charity. Data obtained from 81 NHS trusts using Freedom of Information requests found 48% did not have a formal aftercare pathway that included psychological care. Some 15% reported that they offered no post-treatment support at all, with wide variation according to location.

Almost nine in 10 trusts in the South West had a formal survivorship pathway, compared to just 20% in the East of England. Breast cancer charity Future Dreams said separate research had found 76% of its users sought emotional support more than two years after completing primary treatment.

Dr Fharat Raja, a consultant medical oncologist and Future Dreams trustee, said: “For many cancer patients, diagnosis is followed by an intense focus on getting through treatment.

“There is rarely the time or space to process how this life-changing event is affecting someone, their family, career and wider life.

“Once treatment ends, many people experience a rush of emotions as they begin to process what they have been through.

“For some, that ‘back to normal’ moment never comes, which is why access to psychological support can be such an important part of recovery.”

Zoe Yessaian, a senior NHS mental health nurse and breast cancer survivor, said she only began to face the psychological impact of her diagnosis after treatment.

She added: “During treatment I was focused on survival. There was always another appointment, another decision and another hurdle to get through.

“It wasn’t until active treatment ended that I really began to process everything that had happened and how much cancer had changed my life.

“Despite working in mental health, I still found the emotional impact of breast cancer incredibly difficult. Cancer had taken away so much of the control I felt I had over my future, which is why support after treatment is so important.

“Recovery doesn’t simply begin and end with the physical side of cancer.”

The Express Cancer Care crusade has highlighted the need for better mental health support for cancer patients since January 2025.

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Reporter Robert discovered support was lacking after his diagnosis (Image: Jonathan Buckmaster)

Reporter Robert Fisk spearheaded the campaign after witnessing how too many people were falling through the cracks during his own treatment for stage four bowel cancer.

He exposed how NHS holistic needs assessments — questionnaires that identify a patient’s physical, emotional, social, spiritual, and practical concerns — were not being used consistently.

The campaign led to the announcement in February that every cancer patient will be given a Personalised Cancer Plan to help them cope with the psychological toll, under Labour’s National Cancer Plan.

However, charities have warned that this promise must be fully implemented to be effective.

Macmillan Cancer Support’s chief executive Gemma Peters said in March that potential barriers included staff training and leadership commitment, adding: “Do hospital leaders really see it as being important?”

Future Dreams chief executive Sam Jacobs said: “These findings paint a worrying picture of the support available to cancer patients once treatment ends.

“As the Government develops its National Cancer Plan, survivorship support must become a core part of cancer care rather than something patients have to navigate alone.”

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Climate ChangeRecent Post

Global boom in livestock farming since 2006 is piling pressure on nature, report finds | Farming

by David Jones 02/07/2026
written by David Jones

The number of mammals and poultry farmed worldwide has increased by half in the last two decades, research shows, and the amount of cropland used for feeding livestock has increased by about a quarter.

These increases are putting rising pressure on natural systems, threatening wildlife and plant species and adding to the climate crisis.

The rising demand for meat comes at a time when agricultural land is already becoming less fertile, with an area the size of Canada now suffering degradation. This situation is worsening: about 90% of water withdrawn from natural systems for irrigation is used to grow animal feed.

Global per capita meat supply per year, kg

These findings, from an alliance of campaigning organisations called Stop Financing Factory Farming, come 20 years after the publication of the UN Food and Agriculture Organization’s seminal report on animal farming, Livestock’s Long Shadow. The researchers have updated key aspects of the report, and found that most trends are moving in a negative direction.

Peter Stevenson, the chief policy adviser at the Compassion in World Farming campaign group, told the Guardian that even where progress had been made, for instance by reducing the amount of greenhouse gas produced per unit of meat, it was often outweighed by the sheer increase in the livestock population. Emissions from livestock grew by more than a fifth between 2001 and 2023, according to the FAO. “There’s been a huge increase, and it’s simply because there are so many more livestock now,” he said. About 33 billion livestock mammals and poultry have been added globally in 20 years: there were 94.9 billion farmed animals – the number slaughtered or used for milk or eggs – in 2023, up from 61.8 billion in 2006.

Increasing quantities of fertiliser are being used to produce animal feed, which along with the dumping of slurry is leading to dead zones in seas, with the biggest in the Gulf of Mexico, where marine life is being wiped out across an area the size of Connecticut.

Merel van der Mark, the head of animal welfare and finance at the campaign group Sinergia Animal, said only a widespread shift away from the meat-heavy diets that have become the norm in many parts world would reverse the trend towards greater planetary damage.

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She called on publicly funded development banks, which provided $1.23bn (£930m) to intensive farms in 2024, to lead the charge by changing their investment criteria. “This means a shift away from industrial livestock production, which multilateral development banks must support by stopping financing factory farming and instead aligning their financial flows with a more sustainable world,” she said.

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Art Craft and Leisure newsRecent Post

Graham Norton and Phoebe Waller-Bridge spotted in New York before rumoured Swift wedding

by David Jones 02/07/2026
written by David Jones

Mickey Blank, a celebrity photographer who has been working in New York for over 10 years, told BBC Newsbeat that Madison Square Garden is currently surrounded by members of the press but there’s not actually much to see.

Despite rumours of a red-carpet reception for the expected A-list guests, Blank said she’s not expecting a parade of big-name arrivals.

“It’s like Pentagon-level secrecy,” she said.

“You cannot go in, you cannot see anything.”

“They have an underground parking lot. All the high-profile guests are expected to arrive underground.”

The same applies to seeing Swift herself.

“Your chances of seeing Taylor Swift are, like, lower than zero,” she said.

She added that one of the biggest challenges facing those preparing the venue will be the event that was just staged there.

Blank attended a darts championships at the arena earlier this week, filled with beer-drinking fans, many dressed in costume.

“The floor was so sticky, I could barely move,” she said.

“So I cannot imagine the preparation that goes into that from the darts championship.”

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Local newsRecent Post

MenB vaccine offered to teenagers in the Vale of Glamorgan

by David Jones 02/07/2026
written by David Jones

The vaccination will be made available to 17 and 18-year-olds across Cardiff and the Vale of Glamorgan, as a result of recent outbreaks of meningitis.

Meningococcal group B (MenB) bacteria can cause life-threatening illnesses such as meningitis and septicaemia.

Dr Claire Beynon, executive director of public health at Cardiff and Vale University Health Board, said: “Meningococcal disease can develop very quickly and, although rare, it can have devastating consequences for individuals and families.

“Vaccination is the best way to protect yourself against MenB infection.

“We strongly encourage everyone who is eligible to take up the offer of vaccination and ensure they receive both doses, particularly those preparing to start university or college, where living and socialising in close contact with others can increase the risk of infection.”

Appointment letters will be sent to those born between September 1, 2007, and August 31, 2008.

Vaccinations will be given at Maelfa Wellbeing Hub in Llanedeyrn, Barry Hospital, and Riverside Health Centre.

The first dose will be offered from late July, with a second dose to follow four weeks later.

This is a targeted programme, and only those within the specified age group will be eligible.

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Health newsRecent Post

Turn that light out! Teenagers must to go bed an hour earlier or risk diabetes and obesity say scientists – as blood sugar condition reaches record levels in adolescents

by David Jones 02/07/2026
written by David Jones

Telling a teenager to go to bed early is often a thankless task, typically met with eye rolls and protests.

But scientists say getting a few extra hours of shut-eye could protect youngsters against serious long-term health risks such as type 2 diabetes and obesity.

Researchers from the University of Copenhagen found teens who got even just one extra hour of sleep had fewer fluctuations in their blood sugar levels.

This is important because large swings in blood sugar – scientifically referred to as glucose – can trigger inflammation and place pressure on the body’s metabolic systems. Over time, this can increase the risk of developing serious health conditions like obesity and diabetes.

The number of young people with diabetes has surged globally, with cases doubling over the past 30 years. In England, almost 1,600 children are living with type 2 diabetes – caused by having overly high blood sugar levels.

While a link between sleep and metabolic disease such as diabetes is not new, most previous research has focused on middle-aged adults or people already at increased risk of the condition. 

Authors of the new research, published in the journal SLEEP, however, say their findings suggest that it can also affect young people.

Professor Morten Arendt Rasmussen, from the department of food science at the University of Copenhagen, and the study’s senior author, said: ‘We already know that sleep is important for mental well-being. Our study adds to our understanding of why sleep is also crucial for physical health – and that this applies even early in adulthood.

Turn that light out! Teenagers must to go bed an hour earlier or risk diabetes and obesity say scientists – as blood sugar condition reaches record levels in adolescents

Teenagers sleeping for longer could be protected against serious health complications like type 2 diabetes and obesity, scientists say

‘It also highlights that many of the health problems we tend to see later in life may actually be established much earlier than we previously thought.’ 

The researchers conducted the study by tracking 206 18-year-olds in Denmark for around two weeks using devices that monitored movement, sleep and blood sugar levels. 

For every extra hour of sleep, the teens’ glucose became more stable, with fewer day-to-day fluctuations. 

Meanwhile, average blood sugar rose slightly – by 0.39 milligrams per decilitre mg/dL – a unit which measures blood sugar levels in some nations outside the UK.

Although a rise in blood sugar may not sound like an improvement, it was accompanied by a lower risk of dangerous highs and lows. This suggests overall healthier blood sugar regulation. 

Professor Rasmussen explained: ‘For most 18-year-olds, diabetes feels like something far off in the future. 

‘We’ve known very little about what blood sugar variability means for this age group. But here we’re seeing similar patterns even in completely healthy young adults.’

The research also found that teenagers whose blood sugar fluctuated more during the day tended to sleep for almost seven minutes less the following night, suggesting sleep and blood sugar influence one another. 

David Horner, a postdoctoral researcher from the University of Copenhagen, and the study’s first author, said: ‘So this appears to be a two-way relationship – and that’s new.’

Researchers were also surprised to find that longer sleep was associated with higher blood sugar levels during the morning.

But Professor Rasmussen believes this ‘may actually be beneficial’ because it could ‘help curb sugar cravings and thereby contribute to more stable blood sugar overall’.

Although the study cannot prove that longer sleep directly causes healthier blood sugar regulation, the researchers say it suggests that relatively simple lifestyle changes could have long-term health benefits. 

Professor Rasmussen said: ‘If future studies confirm our findings, sleep could become an even more important factor in preventing disease and promoting health among young people. 

‘And taking action doesn’t require a new diet or an expensive gym membership – it really just comes down to going to bed.’

Around 4.7 million people in the UK are living with a diabetes diagnosis, although Diabetes UK estimates almost 1.3 million have undiagnosed type 2 diabetes. 

Left unmanaged type 2 diabetes can lead to life-altering complications such as heart attacks, strokes, blindness and limb amputations. 

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Art Craft and Leisure newsRecent Post

Katy Perry spikes her fluffy pop with industrial language in Cardiff

by David Jones 02/07/2026
written by David Jones

It may just be me… BUT Katy Perry, longstanding pop royalty that she is, is playing to a sold-out audience at Cardiff Castle, one predominantly full of children with their parents. So when she takes a moment to shout out the C-word – and display it on a massive screen behind her, just to make sure – well, it all seems a little inappropriate and tacky, given the audience demographic.

This came about as part of a sort of question-and-answer game between Perry and the audience, with the American singer reading out answers onstage. Still, if I’d been in attendance with young kids in tow, I would be furious, but it was evidently a part of the show signed off by Perry, presumably in cahoots with her team. A bizarre episode, really, which rather took the shine off what should primarily have been (and still was) a pop extravaganza filled with singalongs and sequins. An early review of the evening seemed rather blasé about it all, save for asides along the lines of “there’ll be some poor parents having to explain that one to their kids…” Well, yes.

Katy Perry - credit Tim Alban

More fervent Katy Perry fans in attendance will doubtless have enjoyed this carry-on more, or have paid it less mind. I was left flummoxed and disappointed by her performance, interspersed as it was by her advice on matters of AI and ramblings about outer space. She is – in an environment such as this one, certainly – someone familiar to millions and in a position to influence young people; the Perry moral compass perhaps needs a reset.

The set in general was neon, pink, fluffy and loud as expected, and festooned with pop culture references. A giant iPhone, water bottle and laptop stood out alongside an array of dancers in cartoonishly buff bodybuilder costumes.

Katy Perry - credit Tim Alban

No question that Katy Perry has done some great pop tunes in her time, and equally little debate that she performed them with gusto to an appreciative Cardiff crowd: California Gurls, Roar and the massive Firework, with which she closed the show. But she – and her set this evening – should have been better, from someone around long enough to know better.

Katy Perry, Cardiff Castle, Tue 30 June

words ANTONIA LEVAY photos TIM ALBAN

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Health newsRecent Post

The 75p supplement that could turbo-charge your weight loss: Drug-free pill can mimic the effect of weight-loss jabs by silencing food cravings

by David Jones 02/07/2026
written by David Jones

An estimated 2.6million people already use weight-loss drugs to tackle stubborn fat.

Last month, a new pill form of Wegovy – the blockbuster slimming jab – was approved for use in the UK in what has been hailed as a game-changing moment for obesity treatment.

Take-up is expected to be huge, with studies suggesting people are twice as likely to opt for a tablet as an injection.

Yet for some, the results can be underwhelming, while others are reluctant to rely on medication at all.

Now experts say a little-known ingredient – known as Amarasate – could offer an alternative, naturally stimulating appetite-suppressing hormones and helping to boost weight loss.

Studies suggest people who take Amarasate, which is rich in bitter compounds, experience less food noise, eat smaller portions and feel fuller for longer.

Amarasate is derived from hops, the plant best known for giving beer its distinctive bitter taste. Researchers believe those same naturally occurring compounds may hold the key to curbing appetite.

‘The bitterness is key,’ says Dr Madusha Peiris, a neurogastroenterologist at Queen Mary University of London.

The 75p supplement that could turbo-charge your weight loss: Drug-free pill can mimic the effect of weight-loss jabs by silencing food cravings

Amarasate comes from hops, a plant cultivated in New Zealand that contains bitter acids which can activate taste receptors in our gut 

‘Most people think taste happens only in the mouth, but the gut is also packed with specialised sensors that can detect compounds in the food we eat.

‘When these sensors are activated, they trigger the release of hormones that influence hunger and fullness, helping to tell the brain when we’ve had enough to eat.

‘The bitter compounds found in hops appear to be particularly effective at activating some of these pathways, including those linked to hormones such as GLP-1. These compounds are largely missing from modern diets, which is one reason researchers are so interested in them.’

So what is Amarasate – and how does it work?

First, it’s important to understand how the body naturally regulates appetite.

While many nutrients are absorbed higher up in the digestive tract, others – particularly fibre – resist digestion until they reach the colon. This is significant because many of the cells responsible for producing appetite-suppressing hormones are concentrated in the lower gut.

‘The more nutrients that reach the lower part of the gut, the more likely you are to feel full for longer,’ says Dr Peiris.

‘What seems to be a big problem for lots of people, especially those struggling to maintain a healthy weight, is food noise – repetitive thoughts about food that can drive snacking and overeating. That often stems from not producing enough of these appetite-suppressing hormones.’

This is where the bitter compounds in Amarasate – sold under the brand name Calocurb – come in.

Amarasate is the active ingredient in Calocurb

Amarasate is the active ingredient in Calocurb

The supplement, which costs around 75p per pill, is designed to deliver its bitter compounds much further down the digestive tract, near the colon, rather than releasing them in the stomach.

There, the compounds effectively trick the gut into thinking an intensely bitter food has arrived, activating receptors that trigger the release of satiety hormones, including GLP-1, peptide YY (PYY) and cholecystokinin (CCK).

These are the same hormones released after eating a diverse, fibre-rich meal. But, as Dr Peiris explains, modern diets often fail to stimulate this response.

‘Highly processed foods, which tend to contain a lot of free sugars and require very little chewing, don’t activate these fullness signals as effectively,’ she says. ‘As a result, we start releasing satiety hormones much later.’

‘Digestion then happens relatively quickly, with food broken down and absorbed before it can reach many of these key receptors further down the digestive tract.’

Weight loss drugs work on some of the same hormonal pathways, but in a much more potent way, flooding the body with synthetic GLP-1 at levels far above those produced naturally.

Research suggests Amarasate may help stimulate the body’s own appetite-regulating systems. A 2022 study published in the American Journal of Clinical Nutrition found that it reduced the number of calories men consumed at mealtimes by almost 20 per cent, while significantly increasing levels of key satiety hormones.

A more recent study involving women produced similar findings, with participants reporting up to a 40 per cent reduction in food cravings.

Another trial, published in Nutrition Journal, followed 200 overweight adults and found those given a bitter hops extract daily had significantly less visceral fat after eight weeks than those receiving a placebo.

Visceral fat is considered particularly dangerous because it accumulates deep inside the abdomen, surrounding organs such as the liver and pancreas and increasing the risk of conditions including heart disease and type 2 diabetes.

After 12 weeks, participants taking the hops extract had lost around seven times more visceral fat than those in the placebo group, while also reducing their overall body-fat levels.

However, experts caution that the evidence remains limited and there is not yet enough research to suggest supplements such as Amarasate could replace prescription weight loss drugs, particularly for patients with obesity-related conditions such as diabetes or sleep apnoea.

Dr Peiris believes the findings nevertheless highlight the importance of naturally stimulating the gut’s appetite-control systems through diet.

‘As a gut scientist who studies nutrient-sensing mechanisms, it’s encouraging to see human studies showing changes in appetite and appetite-regulating hormones,’ she says.

‘But bitter, fibre-rich foods are likely to have a much greater impact because they stimulate these receptors while also nourishing the gut.

‘Humans fundamentally know the kinds of foods they should be eating, but in modern society it’s becoming increasingly difficult to eat a diverse range of fruits and vegetables.

‘It’s that combination of colourful, fibre-rich foods that really helps to support gut health and maximise the release of these satiety hormones.’

This comes amid growing interest in natural ways to activate the same biological pathways targeted by blockbuster weight loss drugs.

Earlier this year, experts told the Daily Mail that psyllium husk – a fibre supplement costing as little as 7p per serving – could help ‘turbo-charge’ the effects of Wegovy and Mounjaro by increasing feelings of fullness, reducing cholesterol levels and potentially helping patients maintain their weight loss after coming off the drugs.

Researchers say both psyllium husk and Amarasate appear to work by stimulating the body’s own appetite-control mechanisms, albeit in different ways.

However experts stress that neither supplement is a replacement for medical treatment.

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