The incident happened on Skomer Road at around 11.20pm on Friday, July 17.
Liam Chichester, 30, from Barry, has been charged with Section 18 grievous bodily harm with intent.
The victim remains in hospital at this time.
A spokesperson for South Wales Police said: “Officers continue to appeal for witnesses following an assault which took place on Skomer Road, Barry, Vale of Glamorgan at around 11:20pm on Friday July 17.
“30-year-old Liam Chichester, from Barry, has been charged with Section 18 grievous bodily harm with intent.
“A 43-year-old man from Barry remains in hospital.
“If you witnessed this incident or recorded any footage, please get in touch”.
Anyone who witnessed the incident or has footage is asked to contact police by calling 101 and quoting reference number 2600229849.
